This fourth generation procreates in the conventional manner, and can result in either a Hybrid, a normal member of the host species or a Purestrain Genestealer, the only manner in which Purestrains can be produced. By the fourth generation, the offspring is barely detectable as alien save for a few give-away signs such as unnaturally sharp teeth and a purplish tinge to the skin.

This cycle continues, with each new generation of Hybrid resembling the host species more closely.

The Hybrid passes on its genetic profile in a similar manner to its Purestrain parent. The offspring of any victim is born as a Hybrid, a corrupt creature exhibiting characteristics of both Genestealer and host species. The victim gains some of the Genestealer's remarkable strength, resilience and longevity, becoming healthier than he was before. This cell behaves like a cancer, altering the host's genetic profile. While the host is thus hypnotized, the Genestealer deposits an egg-like cell that contains the Genestealer's genetic profile. Upon encountering a suitable host, such as a human being, a Genestealer fixes its eyes upon it, mesmerizing it.

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